As a data designer and cartoonist, I have been heavily influenced by Scott McCloud’s book on Understanding Comics. The cool thing about his book is that many of the concepts can be applied very directly to infographics, even those that don’t employ comic style illustration.
This is especially true when dealing with time. Using a comic’s sense of time allows you to tell a program’s complete story in one single infographic. Or you could go in the opposite direction and focus solely on a single important moment in time.